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Original Source: Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorde

Sudhir M Baswan,1,* Allison E Klosner,2,* Kelly Glynn,1 Arun Rajgopal,1 Kausar Malik,1 Sunghan Yim,1 Nathan Stern1

1Innovation and Science, Amway Corporation, Ada, MI, 49355, USA; 2Innovation and Science, Nutrilite Health Institute, Amway Corporation, Buena Park, CA, 90621, USA

*These authors contributed equally to this work

Correspondence: Sudhir M Baswan Amway Corporation, 7575 Fulton St E, Ada, MI 49355, USA
Tel +1-616-787-0216

Abstract: Though there is limited research confirming the purported topical benefits of cannabinoids, it is certain that cutaneous biology is modulated by the human endocannabinoid system (ECS). Receptors from the ECS have been identified in the skin and systemic abuse of synthetic cannabinoids, and their analogs, have also been associated with the manifestation of dermatological disorders, indicating the effects of the ECS on cutaneous biology. In particular, cannabidiol (CBD), a non-psychoactive compound from the cannabis plant, has garnered significant attention in recent years for its anecdotal therapeutic potential for various pathologies, including skin and cosmetic disorders. Though a body of preclinical evidence suggests topical application of CBD may be efficacious for some skin disorders, such as eczema, psoriasis, pruritis, and inflammatory conditions, confirmed clinical efficacy and elucidation of underlying molecular mechanisms have yet to be fully identified. This article provides an update on the advances in CBD research to date and the potential areas of future exploration.

Keywords: cannabidiol, CBD, cannabinoids, endocannabinoids, endocannabinoid system, skin, CB1, CB2, FAAH, AEA

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This article was republished on from the original article, Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorde, which was originally published on 2020-12-07 12:26:15 (based on the date that was listed on the original article at the time it was republished). We shared this article on because our editorial staff believed that its context was useful and helpful to our readers. If you have any questions regarding this article, please email us at .

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